RASAL1 and renal fibrosis: Renal fibrosis was inversely correlated with intrarenal RASAL1 mRNA expression levels (Fig. 10A) and the degree of intrarenal RASAL1 promoter CpG island methylation correlated with the degree of renal fibrosis, irrespective of the underlying disease (Fig. 10B), validating previous studies (Tampe et al., 2014).