The importance of MHPG in DLB as opposed to AD has been emphasized before by Herbert et al. [73], who confirmed that the addition of MHPG to CSF amyloid beta1–42 (Aβ1–42), total- and phosphorylated tau protein improves the discrimination of DLB from AD but not from vascular dementia. The gene discussed is MAPT; the disease is Lewy body dementia.