TPH2 and Anxiety: A significant genotype effect for the time spent in the closed arms (F(2,81) = 3.63, p = 0.031, Fig. 2d), distance on the open arms (F(2,81) = 3.94, p = 0.023, Fig. S3a) and approaching significance for % entries onto the open arms (F(2,81) = 2.75, p = 0.065, Fig. S3b) argue for a reduced anxiety-like phenotype of Tph2−/− mice (all p < 0.1 compared to Tph2+/+ mice).