Risk factors such as C-reactive protein,15 age over 50 years,5 age less than 50 years,4 Charlson comorbidity index,5 history of diverticulitis,4 family history of diverticulitis,8 male sex,16 corticosteroid use,17 and retroperitoneal abscess8 have been associated with recurrence with variable risk. The gene discussed is CRP; the disease is diverticulitis.