MX1 and influenza: It must be noted that in both Davidson and others and Wetzel and others (2014), the pathogenic potential of IFN-αβ during infection was best revealed when mice were deficient in potent virus-specific inhibiting ISGs: Mx1 for influenza (Pavlovic and others 1995; Tumpey and others 2007) and Ifit2 in Sendai.