DZ1 is an LMP1-targeted DNAzyme that down-regulates the expression of LMP1 and inhibits signaling pathways that are abnormally activated by LMP1, thereby increasing apoptosis and inhibiting proliferation and increasing radiosensitivity of NPC cells, which are all substantially enhanced after treatment with a combination of DZ1 and irradiation [18]. Here, PDLIM7 is linked to nasopharyngeal carcinoma.