Immunohistochemical staining showed that MUC1, p-JNK, pSmad3L and c-Myc expression were highly positive in tumor tissues from the SMMC-7721 or NC groups but were weakly positive or even negative in tumor tissues from the MR1-D4 and MR1-D9 groups (Figure 5C). Here, MUC1 is linked to neoplasm.