Cirrhosis was associated with age (p = 0.0011), PNPLA3 genotype (p = 0.0113), AST levels (p < 0.0001), ALT levels (p = 0.0027), albumin levels (p < 0.0001), total bilirubin levels (p = 0.0078), platelet counts (p < 0.0001), prothrombin times (p = 0.0002), hyaluronic acid levels (p = 0.0006), AFP levels (p = 0.0553), PIVKA-II levels (p = 0.0072), and the presence of HCC (p < 0.0001) (Table 3). This evidence concerns the gene PNPLA3 and Cirrhosis.