CHCHD10 and frontotemporal dementia: In a screening of muscle biopsies from patients belonging to a family that presented late-onset myopathy, coupled to motor and cognitive phenotypes, including motor neuron disease and FTD-like symptoms, Bannwarth et al. have identified a missense mutation (S59L) in the nuclear CHCHD10 gene, which encodes for a mitochondrial-resident protein (Bannwarth et al., 2014).