TH and Hypoglycemia: 1996; Bobrovskaya et al. 2010). In contrast, a statistically significant increase in the relative levels of adrenal TH protein was found only in animals exposed to once-daily antecedent recurrent hypoglycemia (RH group, #P < 0.05, Fig.5A), similar to the data reported before (Vietor et al. 1996). Importantly, TH protein following twice daily recurrent hypoglycemia regimen (2RH experimental group) was not significantly different from baseline or from its respective control (2RS, Fig.5A).