One specific epilepsy disorder that has increased risk of sudden death, Dravet Syndrome, is caused by mutations in the Na+ channel SCN1A, which is expressed both in the heart and the brain (Gong et al., 1999; Maier et al., 2002; Maier et al., 2003; Westenbroek et al., 1989). The gene discussed is SCN1A; the disease is Dravet syndrome.