SCN1A and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy: One specific epilepsy disorder that has increased risk of sudden death, Dravet Syndrome, is caused by mutations in the Na+ channel SCN1A, which is expressed both in the heart and the brain (Gong et al., 1999; Maier et al., 2002; Maier et al., 2003; Westenbroek et al., 1989).