BRCA2 and breast carcinoma: Genetic testing is relevant for his at risk relatives, including his sister who was diagnosed at 41 with breast cancer, since studies suggest that woman with BRCA2 mutations have an increased risk of contralateral breast cancer in the absence of intervention [15] and that the risk of ovarian, primary peritoneal and fallopian tube cancer is 11–18 % by age 70 [16, 17].