Anemia is a common comorbidity in patients with chronic heart failure and is associated with an increased all-cause and cardiovascular mortality, reduced exercise capacity due to reduced oxygen carrying and storage capacity, impaired quality of life, a higher risk for hospitalization [12, 13], female gender, older age, edema, low body mass index, increased level of neurohormones, a proinflammatory state (elevated C reactive protein and cytokines), and more comorbidities, including hypertension, atrial fibrillation, diabetes mellitus, and chronic renal failure [14]. Here, CRP is linked to anemia (phenotype).