CXCL8 and endometriosis: In addition, regardless of different sampling design, this result was in part, similar to the in vitro study conducted by Gazvani et al in which the level of IL-8 (a proinflammatory cytokine) in endometrial cell culture from women with endometriosis was remarkably increased specially by high ω-3:ω-6 PUFAs ratio compared with control condition (32).