It has been noted that few other conditions cause papillomatosis or generalized verrucosis to the same degree as GATA2 deficiency, namely Epidermodysplasia verruciformis (EV) warts, hypogammaglobulinemia, immunodeficiency, myelokathexis (WHIM) syndrome warts, immunodeficiency, lymphoedema and anogenital dysplasia (WILD) syndrome, DOCK8 deficiency syndrome and idiopathic CD4 lymphocytopenia (Vinh et al, 2010; West et al, 2014). The gene discussed is GATA2; the disease is lymphedema.