Kaplan-Meier survival curve showed that bladder cancer patients with high PDRG1 expression suffered significantly shorter RFS (log-rank test = 6.578; P = 0.010) and OS (log-rank test = 8.990; P = 0.003) than those with low expression, while multivariate Cox regression analysis demonstrated that PDRG1 was neither independent prognostic variable of RFS (P = 0.457) nor OS (P = 0.145) for bladder cancer patients. This evidence concerns the gene PDRG1 and urinary bladder cancer.