On the other hand, the epithelial to mesenchymal transition (EMT) regulators and mesenchymal markers (ZEB1, ZEB2, TWIST1, NOTCH1, DCLK1, DCN, LIX1L, PMP22, SNAI2, SOX10, TCF4, TSHZ1 and VIM) are under-expressed in BRCA tumors. The gene discussed is LIX1L; the disease is invasive breast carcinoma.