Indeed, the MET regulators (OVOL1, OVOL2, IRF6, ESRP1 and ESRP2) and epithelial markers (CDH1, KRT8, KRT18, ST14, PRSS8, DSP, OCLN, SCNN1A, SPINT1, SPINT2 and TJP3) were over-expressed in BRCA tumors as compared with normal tissues. The gene discussed is IRF6; the disease is invasive breast carcinoma.