CD40LG and dengue disease: One hopeful result is that of the improvement of dengue diagnosis over time, indicated by the significant increase of the IgM confirmation rates from 2002–2005 to 2005–2008 (+15.7%); it concerned the entire consulting population in most of the urban areas (83% with an increase over 9%), which indicates an enhanced identification of the disease at its initial stage whatever the patients’ gender, age, or place of residence.