LGALS1 and infection: In clinical practice, severe EV71-infected patients usually carry a high fever, as well as high virus titers, suggesting that EV71 viruses might be resistant to high temperatures.[3] Since EV71 viruses carried galectin-1 to support their infection, we next tried to investigate whether EV71 virus-bound galectin-1 was able to assist viruses against temperature-induced damage.