Furthermore, the presence of MDSC correlated with improved lung function in CF patients infected with P. aeruginosa. CF-MDSC dampened production of several cytokines, chemokines and growth factors in stimulated PBMC cultures including IL-17A, IFN-γ, IL-13, IL-6, GM-CSF and IL-10 [42]. The gene discussed is IFNG; the disease is cystic fibrosis.