Furthermore, the presence of MDSC correlated with improved lung function in CF patients infected with P. aeruginosa. CF-MDSC dampened production of several cytokines, chemokines and growth factors in stimulated PBMC cultures including IL-17A, IFN-γ, IL-13, IL-6, GM-CSF and IL-10 [42]. This evidence concerns the gene IL13 and cystic fibrosis.