CDH1 and neoplasm: Conversely, the E-cadherin expression was markedly low or lost at mRNA and protein levels in NMIBC tissues, MIBC tissues and high metastatic tumor cell line T24 but significantly high in corresponding adjacent non-neoplastic specimens and BIU-87cell line (Fig. 1A and C; *P < 0.05, **P < 0.001).