For the associations between CaSR polymorphisms and urolithiasis, a total of seven papers which included 10 case-control studies [5, 13–18] for the A986S polymorphism, 9 case-control studies [13–18] for the R990G polymorphism, and 4 case-control [13, 14, 17] studies for the Q1011E polymorphism were involved in this meta-analysis. The gene discussed is CASR; the disease is urolithiasis.