CXCR4 and diffuse large B-cell lymphoma: Furthermore, these signatures largely overlapped the differentially expressed genes (DEGs) identified between CXCR4+ and CXCR4− DLBCL patients with an IPI ≤2 (Supplemental Figure 3I and Table 5), whereas no DEGs were identified between CXCR4+ and CXCR4− DLBCLs with an IPI >2.