KIR2DL1 and cryohydrocytosis: Furthermore, the presence of both the KIR2DS3 and the KIR2DS5 genes with KIR2DL1 gene (Cent-2DS3/5 (1), Table 3) was lower in lymphoproliferative disorders cases compared to CHC cases (6.5 versus 14.4%, p = 0.04, Fig. 3E), and its frequency was about 13.8% in HCV-negative patients.