HLA-B and non-Hodgkin lymphoma: Moreover, a significant negative trend was detected for the 3DL1/HLA-B genotype frequencies in NHL patients (from 42.3% for 3DL1/Bw6-Bw6 to 2.6% for both 3DL1/Bw4-I80-Bw4-I80 and 3DL1/Bw4-T80-Bw4-T80 genotypes, Cochran-Armitage trend test z2 = 1.98, p = 0.047) (Fig. 4).