Sometimes, the benefits demonstrated in the animal models do not come out to be beneficial in humans, for example, the SOD (superoxidase dimutase) gene associated with ALS (Amyotrophic Lateral Sclerosis) allowed the identification of Vitamin E and Creatine to be relievers of the diseased phenotype which failed to cause any improvements in humans (Desnuelle et al., 2001; Groeneveld et al., 2003; Shefner et al., 2004). This evidence concerns the gene SOD1 and amyotrophic lateral sclerosis.