HNRNPA1 and amyotrophic lateral sclerosis: Accordingly, recruitment of FUS, hnRNPA1 and hnRNPA2/B1 to cytoplasmic stress granules was observed in vitro and in a subpopulation of patients with the progressive neurodegenerative disease amyotrophic lateral sclerosis (ALS) (Kim et al., 2013; Li et al., 2013).