Surprisingly, when activated PyCSP-specific and non-specific CD8+ T cells were transferred together in mice infected with Py sporozoites, non-specific CD8+ T cells, which usually did not cluster around Py infected hepatocytes, modified their behavior and were recruited together with PyCSP-specific CD8+ T cells to the site of infection (Cockburn et al., 2013). The gene discussed is CD8A; the disease is infection.