IMP3 and central nervous system cancer: Analysis of public database such as Oncomine (https://www.oncomine.org/resource/login.html) or Rembrandt (http://rembrandt.nci.nih.gov) for IMP3 (gene ID: IGF2BP3) gene expression or gene amplification in human gliomas showed that it was overexpressed by HGGs and specifically by GBM (Table 3 and Figure 3(a)) and also correlated with poor prognosis (Figure 3(b)), thus confirming our protein expression data.