On the contrary, by employing mutation-specific real-time PCR detection studies coupled with fluorescence melting curve analysis, we identified a single case with vulvar superficial spreading primary melanoma, designated as patient 11 in Table 1, harboring the activating mutation BRAFV600E in exon 15 of BRAF, as shown by the additional abnormal peak with a melting temperature of 52.5°C, besides the normal peak with a melting temperature of 59.2°C (Figure 1). The gene discussed is BRAF; the disease is melanoma.