CEACAM5 and neoplasm: In the present meta-analysis, we find that the mean DOR values for CEA, Cyfra21–1, p53 antibody, SCC-Ag and VEGF-C were 16.67, 34.56, 22.88, 24.99 and 7.97, respectively, indicating that, although not as good as expected, measurement of these four tumor markers could be helpful in the diagnosis of EC.