ALK and non-small cell lung carcinoma: Driver mutations in NSCLC include EGFR (epidermal growth factor receptor) [4], K-ras (v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog) [4], ALK (anaplastic lymphoma kinase) [4], ROS1 (c-ros oncogene 1) [4], and Rb (retinoblastoma) [4].