Western blot analysis of lysates containing either all ACC samples (ACC) or all normal adrenal samples (NOR), confirmed the differential expression of Aldehyde-dehydrogenase-6-A1 (ALDH6A1, A), Transferrin (B), Fascin-1 (C), Lamin A/C (D), Adenylate-cyclase-associated-protein-1 (CAP-1, E) and Ferredoxin reductase (FNR, F) in ACC vs. normal adrenals as observed from 2D-DIGE analysis (Fig.4). This evidence concerns the gene FDXR and adrenal cortex carcinoma.