GOLPH3 frequently overexpressed in HCCHigh GOLPH3 expression associated with poor overall survivalGOLPH3 expression correlated with the NF-κB signaling in two HCC patient profilesEctopic GOLPH3 overexpression protects against cisplatin-induced apoptosis in HCC cells. The gene discussed is GOLPH3; the disease is hepatocellular carcinoma.