AKT1 and cancer: More interestingly, the expression levels of c-Myc and c-Jun, two transcriptional factors that favor cell growth and proliferation of cancers [27–29], were also increased accordingly (Figure 2A and 2B), indicating that EBV-miR-BART7-3p stimulated PI3K/Akt/c-myc and c-Jun through suppressing PTEN in NPC cells (Figure 2A and 2B).