ROS1 and non-small cell lung carcinoma: In an ongoing Phase I study, crizotinib treatment resulted in a response rate of 60% (21 out of 35 patients) among patients with advanced ROS1+ NSCLC [Ou SI, et al. Crizotinib therapy for patients with advanced ROS1-rearranged non-small cell lung cancer (NSCLC), WCLC 2013 Meeting, 2013].