NECTIN3 and neoplasm: In the multivariate analysis, the score of nectin-3 (p = 0.015; hazard ratio 0.360; 95 % confidence interval 0.158–0.832) and tumor size (p = 0.014; hazard ratio 0.429; 95 % confidence interval 0.219–0.841) emerged as independent prognostic factors (Table 4).