LAPTM4B and hepatocellular carcinoma: The allele *2 of LAPTM4B was found to be the risk factor of the certain tumors, such as breast carcinoma [37], colon carcinoma [38], hepatocellular carcinoma[39] and gastric carcinoma [40], and LAPTM4B *2 was associated with poor prognosis of breast carcinoma [37], colon carcinoma [38] and hepatocellular carcinoma[39].