As for Alzheimer’s disease, Yahata et al. generated iPSC-derived neuronal cells, which expressed the forebrain marker Foxg 1 and neocortical markers CUX1, SATB2, CTIP2, and TBR1 and also amyloid precursor protein, β-secretase and γ-secretase components. The gene discussed is APP; the disease is Alzheimer disease.