On the basis of several other in vitro studies with a range of NSAIDs and different cancer cell lines, it was concluded that celecoxib and NO-aspirin in the 5–25 μM range were most effective in decreasing cell growth and inducing apoptosis at the lowest dosages and the ability of a particular NSAID to induce the expression of the p75(NTR) protein correlated with its anticancer cytotoxic activity [112,113,114]. This evidence concerns the gene NGFR and cancer.