Herein, we extend those observations to human, IL-1Rrp2 expressing (data not shown), Huh7 hepatocellular carcinoma cells (4.0-fold induction of CCL20 mRNA, 4 h incubation with IL-36γ at 100 ng/ml, n = 3, p = 0.0348, Student's t-test) and human monocyte-derived macrophages (463-fold induction of CCL20 mRNA, 4 h incubation with IL-36γ at 100 ng/ml, n = 5, p = 0.0012, Student's t-test), respectively. Here, CCL20 is linked to hepatocellular carcinoma.