Glioma-associated oncogene 1 (GLI1) is a downstream transcription factor in the hedgehog signaling pathway that reportedly accelerates the progression of various cancers, including basal cell carcinoma [16], colon cancer [17], medulloblastoma [18], gastric cancer [19] and pancreatic carcinoma [20]. Here, GLI1 is linked to exocrine pancreatic carcinoma.