PCAT1 and posterior cortical atrophy: Various mechanisms of lncRNA dependent activation and repression of expression have been reported in PCa, among them are post-transcriptional regulation of BRCA2 by PCAT-1 [31], post-translational regulation of SNF5 protein by SChLAP1 binding [12] as well as mediation of enhancer-promoter looping by interaction with AR (PCGEM1 and PRNCR1, [19]), which is currently disputed and requires further research for clarification [20].