The basal cell loss distinctive of malignant prostatic glands [15] is not responsible for the loss of SNAI2 expression in PCa, as shown by the comparable levels of SNAI2 transcript within basal cells, more differentiated luminal secretory cells, and the whole glandular epithelium, which also means that, in the normal prostatic epithelium, SNAI2 expression is unrelated to the different self-renewal capabilities of the cell compartments. This evidence concerns the gene SNAI2 and posterior cortical atrophy.