The normal glandular epithelium displayed a bright nuclear expression of SNAI2 in both the luminal secretory cells Cytokeratin (CK)18+ and the basal cell CK5.6+ layer (Figure 1B), whereas the neoplastic epithelium (alpha-methylacyl-CoA racemase, AMACR+), from both low- and high-grade PCa foci, was mainly devoid of SNAI2 expression (Figure 1B). This evidence concerns the gene KRT18 and posterior cortical atrophy.