SNAI2 and posterior cortical atrophy: To clarify the biological functions of SNAI2 in human prostate carcinogenesis, we first assessed its expression levels in cell populations microdissected from both epithelial and stromal compartments of PCa foci with low (well differentiated) or high (poorly differentiated) Gleason grade (≤ 3 versus > 3), and from their histologically normal counterparts harvested far from the cancer (Figure 1A and 1B).