Inboth HCC827 and PC9 EGFR-mutant lung cancer cells, three of 14 BH3-domain containingproteins tested showed strongly reduced mRNA induction by erlotinib in the presenceof ectopic SOX2: BIM, BMF, and HRK (but not PUMA) (Figure 6A and Figure 6—figuresupplement 1). This evidence concerns the gene BBC3 and lung cancer.