In natural killer (NK) T cell lymphoma, NFκB is constitutively active and is blocked by curcumin, which induces apoptosis of cancer cells by down regulation of the anti-apoptotic genes induced by NFκB: BCLXL (also known as BCL2L1), cyclin D1 (CCND1), X-linked inhibitor of apoptosis protein (XIAP) and c-FLIP [3,4]. The gene discussed is NFKB1; the disease is cancer.