CD4 and osteogenesis imperfecta: After adjustment for potential confounders in multivariate cox proportional hazard model, the significant (P < 0.05) predictors preventing repeated diagnosing of OI recurrence were being employed in governmental or private sectors, divorced than married, taking prophylaxis at baseline, having a follow-up CD4 count above 100 cells/μL and having hemoglobin value of 10 g/dL and above, whereas not adhering to prophylaxis both at base line and at follow-up was the risk factors for frequent diagnosing of OI recurrence.