CD226 and arthritic joint disease: Of interest, Doppler, which is an accurate tool to measure inflammatory activity in cases of arthritis, did not demonstrate any difference between dnam1+/+ and dnam1−/− mice (scores: 4.2 [3.1-5.4] and 4.9 [4.0-6.5], respectively; p = 0.53) (Figure 5c and d).