Incidence of arthritis increased similarly in both groups during the time (Figure 4b).Median of the mean [± IQR] clinical score was 6.0 [4.6-8.0] in dnam1+/+ mice versus 4.9 [3.6-7.1] in dnam1−/− mice (p = 0.60) (Figure 4c). The gene discussed is CD226; the disease is arthritic joint disease.