Figures 8(A)–8(D) show the effect of HFD alone or HFD and LFD with exercise on the mRNA expression of proinflammatory cytokines IL-1β and TNF-α and proinflammatory marker Hif1α in the colonic mucosa of rats with TNBS-induced colitis fed different diets. This evidence concerns the gene IL1B and colitis.