MTDH and breast cancer: Results taken from in vitro data and findings from the analysis of tissue specimens have confirmed that MTDH expression is significantly higher in cancerous tissue than in peritumoral tissue or normal cells, this comparison includes hepatocellular carcinoma (5,6), malignant glioma (7), breast cancer (8), renal cell carcinoma (9), neuroblastoma cell lines (10) and PC (11–13).