CEBPA and Hyperinsulinemia: These findings are in keeping with an earlier study demonstrating that Rhizoma Atractyloidis acupuncture in HFD-induced obese ICR mice inhibited expression of a number of proteins including C/EBP-α and enhanced the activation of AMPK associated with the inhibition in development of weight gain, hyperglycemia, hyperinsulinemia, and hyperlipidemia as well as the enlargement of fat cell size61.